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Unraveling the Truth: Debunking Myths About Bioidentical Hormone Optimization with Miklos Major

In this podcast episode, Jay is joined by Miklos Major, a functional and family medicine nurse practitioner with extensive knowledge in hormone optimization.

They discuss the current state of hormone therapy and the challenges and scrutiny faced by prescribers of health optimization tools in this category. 

Many physicians are ignorant about how to manipulate hormones to improve the quality of life for their patients, which results in many people being prescribed testosterone who have no business being on it, while others are being denied the benefits of hormone optimization when it could dramatically improve their quality of life.

Jay and Miklos also debunk several common myths around hormone optimization, including misconceptions about the role of estrogen, the (improper) use of GLP-1 agonists, and the value of growth hormone secretagogues (GHS) as alternatives to human growth hormone in some cases.

If you’re looking to gain a deeper understanding of hormone therapy and how you can effectively navigate the modern healthcare system to improve your health and well-being through hormone optimization, you’ll want to give this a listen.

“The average Western trained physician doesn’t understand the difference between optimization and the treatment of pathology.”
– Miklos Major

What You’ll Learn From This Episode

  • The difference between hormone optimization and the treatment of pathology, and how the modern healthcare system gets it wrong.
  • The reality of estrogen’s role in the body and what many practitioners fail to get right about managing it in patients.
  • The significance of hormone levels and lab reference ranges, and how they impact your overall well-being.
  • The potential of GLP-1 agonists for weight loss and how they could be a game-changer in achieving your health goals.
  • The difference between growth hormone secretion and synthetic growth hormone, and the appropriate usage of each.
  • Where to go for more information about how to manage your individual hormone optimization with the help of a qualified practitioner.


Key Moments In This Conversation

  • 00:00:00 – Introduction 
  • 00:03:48 – Challenges and Limitations Of Most Hormone Optimization Approaches
  • 00:05:35 – Misconceptions About The Role of Estrogen & Its Health Impact
  • 00:17:23 – Controversy Surrounding the Use of AI for Hormonal Optimization 
  • 00:19:59 – Biochemical Uniqueness and Individualized Treatment 
  • 00:28:07 – GLP-1 Agonists, Their Application, And Considerations
  • 00:38:14 – Comparison of Human Growth Hormone (HGH) and Growth Hormone Secretagogues (GHS)
  • 00:42:41 – Age and Human Growth Hormone 
  • 00:50:10 – Conclusion and Where To Follow Miklos


Guest Bio

Miklos Major is a functional and family medicine nurse practitioner who has become well-known for his expertise in hormone optimization and hormone therapy.

With multiple doctorates and decades of treatment experience, Miklos has extensive knowledge in the field.

He currently operates an independent practice called Apex Integrative Medicine, PLLC.

Miklos’ dedication to evidence-based practice and his commitment to providing optimal care for his patients have earned him a reputation as a trusted and knowledgeable practitioner in the field of hormone optimization.

Through his work, he aims to empower individuals to take control of their health and improve their overall well-being.

You can follow Miklos and his work at


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