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Changing the Paradigm Shift of Hormone Optimization – Part 1 with Dr Keith Nichols & Dr Scott Howell

There are many hurdles and roadblocks getting in the way of quality optimization reaching the patients who need it.

How is a lack of physician awareness contributing to this issue?

What are the mechanisms that interfere with androgen metabolism and distribution in the body?

On this episode, Dr. Keith Nichols and Dr. Scott Howell from Tier 1 Health and Wellness, share on the work they are doing to redefine testosterone optimization and how it benefits patients.

We focus on optimization, and we want individuals to have a health based paradigm, not a chemical-based living paradigm. -Dr. Scott Howell

At the start of the show, Keith and Scott shared a background on how they got started in the optimization space, and reasons for the lack of physician awareness when it comes to hormone optimization.

Next, we discussed the importance of statistical literacy in physicians and why we need to stop being a lab-centric society.

We also discussed:

  • Why misinformation and misrepresentation of credentials is so bad for optimization
  • The importance of physicians integrating evidence into their practice
  • Why optimization patients need to have realistic expectations at the start of therapy

Three Takeaways

When it comes to testosterone optimization, you have to outcompete the receptors.

There’s no limiting dose of testosterone to get a man to feel better.

What Tier 1 defines as optimal:

  • Feel your best
  • Function your best
  • Perform your best
  • At Your Healthiest

30-40% of physicians don’t have statistical literacy, which is a huge problem.

The principles of harm reduction: education, guidance, genetic testing, risk mapping and auxiliary drugs.

Guest Bio-

John Keith Nichols, M.D. is the Medical Director and CEO of Tier 1 Health and Wellness, the premier preventive medicine clinic in the Southeast.

Scott Howell, Ph.D. is the Research Director of Tier 1 Health and Wellness, Center for Clinical Research.

He is an epidemiologist, exercise physiologist and mechanical engineer with research interests in the long-term safety of therapeutic androgen use, endocrine disrupting chemicals exposure, and preventative medicine.

For more information, visit

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