- Jay's Protocol
Jay Campbell's Beauty, Skin & Rejuvenation Protocol
Younger skin from the inside out. Compounds that work at the cellular level — not the surface.
Goal: Cellular Repair, Collagen Support & Deep Skin Rejuvenation
- Protocol Overview
This isn’t a skincare routine.
It’s a science-backed stack for men and women who want to address skin aging where it actually starts — at the level of cellular repair, collagen synthesis, immune regulation, and mitochondrial function.
The compounds in this protocol work systemically. The results show up in your skin, your recovery, and how you feel from the inside out.
Compounds
7
Protocol Duration
8–12 weeks (Thymalin & Epitalon follow 20-day cycles — see individual notes)
Administration
Mixed
Best For
Men and women 35+,
intermediate to advanced
This protocol is for you if:
- You've done the basics — diet, sleep, training — and want to address aging at a deeper level
- You want to support collagen production, skin quality, and cellular regeneration from the inside out
- You're committed to running compounds the right way, with bloodwork and proper cycle structure
- You're already familiar with peptide administration or have completed the Quantum Peptides course
This protocol is NOT for you if:
- You've never reconstituted or injected peptides — start with the Reconstitution Course first
- You haven't had recent bloodwork done
- You're expecting cosmetic-level results without the lifestyle work to back it up
The Compounds
GHK-Cu
What It Does: A naturally occurring copper peptide with a well-documented role in collagen synthesis, wound healing, and skin remodeling. GHK-Cu stimulates the production of collagen, elastin, and glycosaminoglycans while activating antioxidant and anti-inflammatory pathways — making it one of the most studied peptides for skin repair and rejuvenation.
Protocol Details:
Dose
1.7mg
Timing
AM
Frequency
Every day
Duration
8 weeks on, 8 weeks off
Administration
SubQ injection
Source
Jay’s Note: GHK-Cu is the anchor of this entire stack. Most people know it from topical skincare — but systemic administration is a different level entirely. This is the compound that drives the collagen remodeling and tissue repair everything else builds on.
GLOW (BPC-157 / TB-500 / GHK-Cu Blend)
What It Does: A three-compound healing blend combining BPC-157’s tissue repair and gut-healing properties, TB-500’s systemic regeneration and anti-inflammatory action, and GHK-Cu’s collagen synthesis and skin remodeling effects. Together they create a repair signal that works at the level of soft tissue, connective tissue, and skin simultaneously — accelerating recovery and rebuilding structural integrity from multiple angles at once.
Protocol Details:
Dose
2.5mg / 500mcg / 500mcg
Timing
AM or PM
Frequency
5 days on, 2 days off
Duration
8 weeks on, 8 weeks off
Administration
SubQ injection
Source
Jay’s Note: GLOW is the repair workhorse of this protocol. You’re getting BPC-157, TB-500, and GHK-Cu in a single injection — three compounds that each have strong individual track records for tissue healing and skin quality, stacked together and hitting all three mechanisms at once. This is the compound that keeps the repair signal running between the longevity cycles.
NAD+
What It Does: NAD+ is a coenzyme essential to mitochondrial energy production and DNA repair. Levels decline with age — and that decline shows up in your skin as reduced cellular turnover, compromised barrier function, and slower healing. Replenishing NAD+ through injection restores the cellular energy machinery that keeps skin cells functioning the way they should.
Protocol Details:
Dose
100mg
Timing
AM
Frequency
2–3 days per week
Duration
As needed
Administration
SubQ injection
Source
Jay’s Note: NAD+ isn’t a skincare compound — it’s a cellular energy compound. But when your cells have the fuel they need to repair and replicate properly, your skin reflects that. This is foundational to everything else in this protocol working the way it’s supposed to.
Vilon
What It Does: A dipeptide bioregulator with documented effects on immune function, inflammation control, and tissue repair. Vilon works at the thymus level to regulate immune signaling and supports the body’s capacity to maintain and repair connective tissue — mechanisms that directly affect skin quality, elasticity, and healing speed.
Protocol Details:
Dose
0.5–2mg daily
Timing
SubQ or IM
Frequency
Daily
Duration
8–12 weeks on, 6 weeks off
Administration
SubQ or IM injection
Source
Jay’s Note: Vilon is the immune regulation layer of this stack. Chronic low-grade inflammation is one of the primary drivers of accelerated skin aging — Vilon helps bring that baseline down so the repair compounds can actually do their job.
Regeno Blend (BPC-157 / TB-500 / Cartalax)
What It Does: A healing, immunity, and longevity blend that pairs BPC-157 and TB-500’s tissue repair and regenerative signaling with Cartalax — a peptide bioregulator targeting cartilage and connective tissue health. This combination extends the repair scope of the protocol deeper into structural tissue, supporting skin elasticity and the underlying connective framework that keeps skin looking and behaving younger.
Protocol Details:
Dose
500mcg / 1mg
Timing
AM
Frequency
5 days on, 2 days off
Duration
8 weeks on, 8 weeks off
Administration
SubQ injection
Source
Jay’s Note: Where GLOW handles surface-level skin remodeling, Regeno goes after the connective tissue underneath it. Cartalax is a compound most people in the biohacking space haven’t paid enough attention to yet. Adding it to the BPC-157/TB-500 base makes this blend genuinely different from anything else in this protocol category.
Thymalin
What It Does: A thymic peptide bioregulator with well-documented immunomodulatory and longevity-promoting effects. Thymalin restores thymic function, which declines sharply after age 40 — and with it, the immune-mediated repair processes that govern tissue regeneration. Running Thymalin in 20-day cycles supports the immune infrastructure your skin relies on to rebuild itself.
Protocol Details:
Dose
2mg
Timing
PM
Frequency
Every day
Duration
20 days in a row, 3x per year
Administration
SubQ injection
Source
Jay’s Note: Thymalin and Epitalon are run together as a 20-day longevity cycle — this is exactly how the original Khavinson research was structured. Don’t separate them. Don’t extend the cycle. Twenty days, three times a year, and you’re letting the biology work the way it was designed to.
Epitalon
What It Does: A tetrapeptide bioregulator derived from the pineal gland with documented effects on telomere elongation, melatonin regulation, and cellular aging. Epitalon is one of the most studied longevity compounds in existence — with research going back decades showing its ability to slow the biological markers of aging at the cellular level. In the context of this protocol, it’s the systemic anti-aging anchor that complements everything else targeting the skin directly.
Protocol Details:
Dose
2mg
Timing
PM
Frequency
Every day
Duration
20 days in a row, 3x per year
Administration
SubQ injection
Source
Jay’s Note: Epitalon is the deepest longevity lever in this stack. Telomere shortening is one of the core mechanisms of cellular aging — and Epitalon is the only peptide with credible research showing it can actually address that. Run it with Thymalin every time, PM dosing, 20 days straight.
How to Run This Protocol
01
Before You Start:
- Get bloodwork done. You need a baseline before you add anything to your system.
- Without it, you're guessing — and guessing is how people miss what's working and ignore what isn't.
02
Running the Stack:
- Follow each compound's individual cycle timing exactly as written.
- Don't compress the off-weeks and don't extend the on-weeks because you're feeling good.
- The cycle structure isn't arbitrary — it's how you maintain receptor sensitivity and keep the compounds working the way they're supposed to.
03
What to Track:
- Run follow-up bloodwork at the six-week mark and again at protocol completion.
- Track your numbers alongside how you actually feel — energy, sleep quality, recovery between sessions, and body composition changes.
04
Common Mistakes:
- Starting without a baseline. If you don't know where you started, you can't know what moved.
- Abandoning the protocol too early. Most of these compounds need four to six weeks before you feel the full effect.
- Skipping the off-weeks. The off-weeks are part of the protocol.
Frequently Asked Questions
How long before I see results?
GHK-Cu and Vilon typically produce noticeable changes in skin texture and tone within four to six weeks
Epitalon and Thymalin operate at the cellular level — the results are cumulative across multiple 20-day cycles over months and years, not something you observe after a single run.
Track your skin quality, energy, and recovery markers alongside formal bloodwork. Don’t rely on the mirror alone.
Can women run this protocol?
Yes — this stack was designed with both men and women in mind.
GHK-Cu, NAD+, Vilon, Thymalin, and Epitalon are not hormone-dependent compounds. They work on tissue repair, immune function, and cellular longevity mechanisms that apply regardless of sex.
Get baseline bloodwork done before starting, and track inflammatory markers alongside standard labs.
Can I run this alongside TRT or HRT?
Yes.
None of the compounds in this protocol interfere with testosterone or estrogen replacement therapy. GHK-Cu actually complements hormonal optimization — collagen synthesis is hormone-dependent, and running it alongside optimized hormones amplifies the tissue remodeling response.
Get bloodwork at the six-week mark to confirm your markers are tracking where you want them.
Do Thymalin and Epitalon need to be run together?
Run them together.
The 20-day concurrent cycle structure mirrors the original research protocols — and the synergy between thymic immune regulation (Thymalin) and pineal-level cellular repair (Epitalon) is part of why the results hold up. Separate them and you’re leaving efficacy on the table.
Get Fully Optimized with Jay
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