An increasing number of athletes and bodybuilders in the peptides industry are considering a CJC-1295 & Ipamorelin stack for building muscle.
But why?
This powerful peptide duo can not only help you shed stubborn fat and promote muscular hypertrophy, but many users also report improved sleep quality and faster recovery times.
And when used correctly, this peptide combination has a solid safety profile with few yet tolerable side effects.
But how does stacking Ipamorelin and CJC-1295 increase both strength and added lean mass?
In this article, we’ll explore the mechanisms powering the CJC-1295 and Ipamorelin stack.
We’ll also share testimonials from people who have experienced the transformative benefits of using CJC-1295 and Ipamorelin together.
What is CJC-1295?
CJC-1295 is a peptide with a similar structure to growth hormone-releasing hormone (GHRH).
This growth hormone secretagogue helps increase levels of human growth hormone in the blood (plasma) by up to ten times the normal levels (i.e. relative to what the body can naturally produce).
It can also increase the levels of serum growth hormone by 200-1000%, which usually lasts for up to 6 days.
(NOTE: Plasma and serum are two different things — go here and here for more info)
Since the peptide has a similar structure to GHRH, it not only prompts the pituitary gland to secrete growth hormone but also secretes anabolic hormones such as insulin-like growth factor 1 (IGF-1).
This makes CJC-1295 an ideal peptide for more muscle growth, improved strength and enhanced physical performance.
What is Ipamorelin?
Ipamorelin is a growth hormone-releasing peptide (GHRP) and a growth hormone secretagogue composed of five amino acids.
It mimics the release of the hunger hormone ghrelin along with growth hormone.
Most importantly, Ipamorelin does so without affecting the release of other hormones in the body such as cortisol, aldosterone, acetylcholine, and prolactin.
This makes the peptide one of the safest and most effective forms of growth hormone replacement therapy used to manage various disease states, improve athletic performance, promote anti-aging, and resolve growth hormone deficiencies.
Compared to other peptide therapies, Ipamorelin is more potent as it can optimize growth hormone release for a longer period of time.
It works by sending a selective pulse to the pituitary gland, which secretes growth hormone within the body. This helps in the growth and development of muscle tissue without the risk of any cartilage or bone deformities.
Additionally, Ipamorelin also promotes cell synthesis while boosting insulin and ghrelin levels, all of which are important for building muscle and losing fat.
And best of all, Ipamorelin also works just as well in women as it does in men with respect to improving body composition.
The Science Behind Stacking CJC-1295 and Ipamorelin
A CJC-1295 and Ipamorelin stack is a great way to maximize your muscle-building efforts.
The peptide CJC-1295 takes at least 1 to 4 hours to reach peak blood serum levels, while Ipamorelin works much quicker as it is cleared and secreted from the body within 2 hours.
When you use the peptides CJC-1295 and Ipamorelin together, they team up to boost your body’s growth hormone production in two key ways.
The first way is more frequent GH pulses.
CJC-1295 can keep the GH-releasing hormone active for longer, leading to more frequent bursts of growth hormone.
The peptide mimics how your body naturally releases growth hormones when you were younger.
The second way is stronger GH surges.
Ipamorelin boosts GH release by targeting the pituitary receptors to pump up the volume of secreted growth hormone, resulting in significant increases in your overall GH levels.
In other words, Ipamorelin creates spikes of GH while CJC-1295 extends the time your body keeps pumping it out.
Benefits of the CJC-1295 & Ipamorelin Stack
Discover how stacking the peptides CJC-1295 and Ipamorelin can help improve your muscle gains and your overall well-being.
Increased Muscle Mass
Stacking Ipamorelin and CJC-1295 is primarily done by bodybuilders to achieve the end goal of increased muscle mass.
Ipamorelin can do so by upregulating muscle tissue regeneration and protein synthesis, especially after a musculoskeletal injury.
CJC-1295, as discussed earlier, maintains elevated GH levels and this leads to extended muscle growth stimulation.
So in theory, both support muscle growth and hypertrophy while shortening the time for muscle recovery following intense physical activity.
In a study published in The Journal of Clinical Endocrinology & Metabolism, test subjects who were given CJC-1295 reported increased strength and muscle mass after 14 weeks of use:
“To investigate whether age-related deficits in the somatotropic axis limit the degree to which muscle strength can improve with resistance training in older individuals, we conducted a double blind, placebo-controlled exercise trial.
Eighteen healthy elderly men (65-82 yr) initially underwent progressive weight training for 14 weeks to invoke a trained state.
Subjects were then randomized to receive either 0.02 mg/kg BW.day recombinant human GH (rhGH) or placebo, given sc, while undertaking a further 10 weeks of strength training.
Sequential measurements were made of muscle strength (one repetition maximum), body composition (dual energy x-ray absorptiometry), and circulating levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3.
For each exercise, strength increased for both groups (P = 0.0001) through 14 weeks of training, with little improvement thereafter. Increases in muscle strength ranged from 24-62% depending on the muscle group.
Baseline plasma IGF-I concentrations were similar in both groups (mean +/- SEM, 106 +/- 9 micrograms/L), approximately half that observed in healthy young adults.
In the rhGH group, IGF-I levels increased to 255 +/- 32 micrograms/L at week 15 and 218 +/- 21 micrograms/L at week 24 (P < 0.001). In the placebo group, IGF-I increased slightly to 119 +/- 6 micrograms/L at 24 weeks.
IGF-binding protein-3 also increased in the rhGH group (P < 0.05). rhGH had no effect on muscle strength at any time, and no systematic difference in muscle strength was observed between groups throughout the study.
Body weight did not change in either group, but lean body mass increased, and fat mass decreased (P < 0.05) in the rhGH group.
Supplementation with rhGH does not augment the response to strength training in elderly men.
These results suggest that deficits in GH secretion do not underlie the time-dependent leveling off of muscle strength seen with training in the elderly and provide no support for the popular view of GH as an ergogenic aid.”
Similarly, the use of growth hormone-releasing peptides like CJC-1295 and Ipamorelin can help promote weight gain and muscle mass in patients with anorexia nervosa.
In fact, test subjects gained 6.7 kg and improved muscle strength after 14 weeks of taking GHRP-2:
“We administered GHRP-2 to a patient with a 20-year history of anorexia nervosa to determine whether GHRP-2 treatment increases food intake and body weight.
GHRP-2 was administered before every meal by an intranasal approach for 1 year.
Although the patient reported a decreased fear of eating and decreased desire to be thin by our previous treatment, she was unable to increase food intake or body weight because of digestive tract dysfunction.
Vomiting after meals caused by delayed gastric emptying and incurable constipation were prolonged, and sub-ileus and hypoglycemia were observed.
GHRP-2 increased the feeling of hunger and food intake, decreased early satiety and improved hypoglycemia. The patient’s body weight gradually increased by 6.7 kg (from 21.1 kg to 27.8 kg) in 14 months after starting GHRP-2 administration.
The fatigability and muscle strength improved, and the physical and mental activities were also increased. No obvious side effects were observed after long-term intranasal administration of GHRP-2.
Patients with a long-term history of eating disorder occasionally recover from the psychological problems such as fear for obesity but remain emaciated.
We believe that ghrelin agonists such as GHRP-2 may be promising agents for the effective treatments of severe anorexia nervosa in a chronic condition.”
Accelerated Fat Loss
The use of the peptides CJC-1295 and Ipamorelin can promote weight loss by boosting fat breakdown and metabolism.
Ipamorelin supports fat oxidation and metabolic activity, while CJC-1295 improves the body’s ability to tap into fat storage for energy.
As a result, you can lose body fat and achieve improved body composition.
One study had test subjects with HIV-associated lipodystrophy use a recombinant human growth hormone (such as CJC-1295) and the end result was lost weight and visceral fat alongside improved skeletal muscle after 12 weeks of administration:
“HIV-associated lipodystrophy often includes excess accumulation of visceral fat.
Recombinant human growth hormone (rhGH) is a potential treatment for the excess visceral fat.
Prospective, open-label trials of 24 weeks of rhGH 6 mg/d and 24 weeks of 4 mg every other day were conducted with an intervening washout period of 12 weeks.
Thirty HIV-positive participants (26 men and 4 women) with visceral adiposity were enrolled.
The main outcome measure was change in visceral adipose tissue (VAT) on whole-body magnetic resonance imaging scan.
Changes in whole body subcutaneous adipose tissue and skeletal muscle, glucose metabolism, serum lipids, and quality of life were also assessed.
Despite stable body weight, VAT decreased in evaluable subjects an average of 42% with rhGH 6 mg/d (n = 24; p < .001) and 15% with 4 mg every other day (n = 10; p < .01) after 12 weeks, with trends toward further decreases after an additional 12 weeks at each dose.
Subcutaneous adipose tissue also decreased, but proportionately less and not significantly on the lower dose.
Skeletal muscle increased. Body composition rebounded to or near baseline after the washout period.”
In another study published in Hormone Research in Paediatrics, 12 obese test subjects who took CJC-1295 reported reduced body weight and increased lean body mass compared to the placebo group:
“We investigated the effects of GH treatment and dietary restriction on lipolytic and anabolic actions, as well as the consequent changes in insulin and GH secretion in obesity.
24 obese subjects (22 women and 2 men; 22–46 years old) were fed a diet of 25 kcal/kg ideal body weight (IBW) with 1.2 g protein/kg IBW daily and were treated with recombinant human GH (n = 12, 0.18 U/kg IBW/week) or placebo (n = 12, vehicle injection) in a 12-week randomized, double-blind and placebo-controlled trial.
GH treatment caused a 1.6-fold increase in the fraction of body weight lost as fat and a greater loss of visceral fat area than placebo treatment (35.3 vs. 28.5%, p < 0.05).
In the placebo group, there was a loss in lean body mass (–2.62 ± 1.51 kg) and a negative nitrogen balance (–4.52 ± 3.51 g/day).
By contrast, the GH group increased in lean body mass (1.13 ± 1.04 kg) and had a positive nitrogen balance (1.81 ± 2.06 g/day).
GH injections caused a 1.6-fold increase in IGF-I, despite caloric restriction.
GH response to L-dopa stimulation was blunted in all subjects and it was increased after treatment in both groups.
GH treatment did not induce a further increase in insulin levels during an oral glucose tolerance test (OGTT) but significantly decreased free fatty acid (FFA) levels during OGTT.
The decrease in FFA area under the curve during OGTT was positively correlated with visceral fat loss.
This study demonstrates that in obese subjects given a hypocaloric diet, GH accelerates body fat loss, exerts anabolic effects and improves GH secretion.”
Better Recovery Times
Growth hormone-releasing peptides such as CJC-1295 and Ipamorelin can speed up recovery caused by physical injury or sports trauma.
This makes them some of the best peptides for athletes whose entire livelihoods can be ended permanently by a single devasting injury.
Both peptides work by promoting the release of IGF-1 and GH, therefore boosting tissue regeneration.
They also increase collagen production — which speeds up the healing of wounds — as shown in a study published in the Tissue Engineering and Regenerative Medicine Journal:
“In the present study, porous PLGA microparticulate scaffolds (PMS_P), surface-hydrolysed scaffolds (PMS_Hyd) and cytomodulin-coupled scaffolds (PMS_CM) were prepared and characterized.
After coupling the particles with cytomodulin, the size was reduced from 334 µm (span 0.53) to 278 µm due to hydrolysis, and contact angle also decreased from 70.87 ± 8.56 to 31.43 ± 7.43, indicating an increase in hydrophilicity.
Surface roughness and pore density increased, along with an increase in surface area from 9.59 ± 0.36 to 16.82 ± 0.064 m2/g after attaching the biomolecule CM onto the PLGA particles.
In vitro cell culture experiments on human dermal fibroblasts (HDFs) were performed for 21 days, in which MTT assay indicated two-fold higher cell proliferation on PMS_Hyd than on PMS_CM; however, cell distribution, cell spreading and actin production were significantly higher on PMS_CM than on other scaffolds.
Migration of cells from PMS_CM to a 2D plate was gradual but the migrated cells attained early confluence, indicating the preservation of normal cellular functions. In a full-thickness wound mouse model, PMS_CM exhibited 80% wound closure within 2 weeks.
Further, at the end of week 3, the inflammatory cell count in the PMS_CM group was reduced to one-third of the control group, while in PMS_P and PMS_Hyd the extent of inflammation was much higher and more severe.
In the case of PMS_CM, abundant fibroblast proliferation, early formation of the scar tissue, eschar formation and inward movement of the wound margins (a zipper-like movement) towards the deeper layers of the skin suggested advanced wound healing.
Cytomodulin-coupled scaffolds ensured better cell spreading and migration and thus enabled rapid wound healing.”
Moreover, in a study published in The Journal of Physiology, CJC-1295 was shown to support tendon repair.
After just 14 days of administration, it improved tendon collagen protein synthesis by 1.3 times and increased tendon collagen I mRNA expression by 3.9 times, boosting the body’s ability to repair damaged tissue:
“Tendon collagen I mRNA expression and tendon collagen protein synthesis increased by 3.9-fold and 1.3-fold, respectively (P < 0.01 and P= 0.02), and muscle collagen I mRNA expression and muscle collagen protein synthesis increased by 2.3-fold and 5.8-fold, respectively (P < 0.01 and P= 0.06).
In skeletal muscle and tendon the extracellular matrix confers important tensile properties and is crucially important for tissue regeneration after injury.
Musculoskeletal tissue adaptation is influenced by mechanical loading, which modulates the availability of growth factors, including growth hormone (GH) and insulin-like growth factor-I (IGF-I), which may be of key importance.
To test the hypothesis that GH promotes matrix collagen synthesis in musculotendinous tissue, we investigated the effects of 14 day administration of 33–50 μg kg−1 day−1 recombinant human GH (rhGH) in healthy young individuals.
rhGH administration caused an increase in serum GH, serum IGF-I, and IGF-I mRNA expression in tendon and muscle.
Tendon collagen I mRNA expression and tendon collagen protein synthesis increased by 3.9-fold and 1.3-fold, respectively (P < 0.01 and P= 0.02), and muscle collagen I mRNA expression and muscle collagen protein synthesis increased by 2.3-fold and 5.8-fold, respectively (P < 0.01 and P= 0.06).
Myofibrillar protein synthesis was unaffected by elevation of GH and IGF-I. Moderate exercise did not enhance the effects of GH manipulation. Thus, increased GH availability stimulates matrix collagen synthesis in skeletal muscle and tendon, but without any effect upon myofibrillar protein synthesis.
The results suggest that GH is more important in strengthening the matrix tissue than for muscle cell hypertrophy in adult human musculotendinous tissue.”
Anti-Aging
The use of growth hormone therapy, such as stacking CJC-1295 and Ipamorelin, produces a steady and longer release of human growth hormone.
This provides anti-aging benefits such as improved sex drive, higher energy levels, and boosted cognitive health.
It’s no wonder why some people consider these peptides to be akin to the fountain of youth!
A study published in The Journal of Urology revealed that erectile dysfunction and low libido are strongly linked to growth hormone deficiency.
Logically, boosting GH levels should help reverse some of the symptoms of male sexual dysfunction.
In men with erectile dysfunction, those given growth hormone had increased erections and improved sexual function compared to the placebo group:
“Ten men with erectile dysfunction of no known organic cause were entered in a double-blind, placebo controlled crossover study in which the erectogenic properties of Melanotan-II and a vehicle placebo were compared using real-time RigiScan monitoring.
The presence, duration and rigidity of erections were recorded during a 6-hour period.
In 8 of 10 men treated with Melanotan-II clinically apparent erections developed.
Mean duration of tip rigidity greater than 80% was 38.0 minutes with Melanotan-II and 3.0 with placebo (p=0.0045).
Transient side effects of nausea, stretching and yawning, and decreased appetite were reported more frequently after injections of Melanotan-II than placebo but none required treatment.
Melanotan-II is a potent initiator of erections in men with psychogenic erectile dysfunction and has manageable side effects at a dose of 0.025 mg./kg.”
Growth hormone-releasing peptides like CJC-1295 and Ipamorelin can also enhance cognitive function and memory.
How?
Through the same way the other benefits have been achieved: Boosting growth hormone levels in the body.
Growth hormones also play a crucial role in promoting neurogenesis, synaptic plasticity, and neuronal survival, all three of which are essential for optimal and healthy brain function.
By supporting these processes, these peptides help improve memory, mental clarity, and learning abilities.
This is especially important for older adults who are more susceptible to age-related cognitive decline.
Adults with memory problems who were given GHRH showed improvement in their verbal memory and had a lower risk of impaired cognitive function, as evidenced in a Neurobiology of Aging paper:
“In healthy older adults, GHRH supplementation ameliorated cognitive impairment associated with aging and Alzheimer’s disease. [86]
Declines in the activity of the somatotrophic axis have been implicated in the age-related changes observed in a number of physiological functions, including cognition.
Such age-related changes may be arrested or partially reversed by hormonal supplementation.
We examined the effect of 6 months treatment with daily growth hormone releasing hormone (GHRH) or placebo on the cognition of a group of 89 healthy older (68.0 ± 0.7) adults. GHRH resulted in improved performance on WAIS-R performance IQ (p < 0.01), WAIS-R picture arrangement (p < 0.01), finding A’s (p < 0.01), verbal sets (p < 0.01) and single–dual task (p < 0.04).
GHRH-based improvements were independent of gender, estrogen status or baseline cognitive capacity.
These results demonstrate that the age-related decline in the somatotrophic axis may be related to age-related decline in cognition.
Further they indicate that supplementation of this neuro-hormonal axis may partially ameliorate such cognitive declines in healthy normal older adults and potentially in individuals with impaired cognitive function (i.e., mild cognitive impairment and Alzheimer’s disease).’
Sleep Quality
Ipamorelin and other growth hormone-releasing peptides like CJC-1295 are useful for treating sleep disorders and achieving restful sleep.
To nobody’s surprise, increasing GH and IGF-1 levels can enhance your body’s sleep processes, leading to better sleep quality and quantity.
Researchers have found that using growth hormone-releasing hormone (GHRH) peptides like CJC-1295 and Ipamorelin can enhance stage 2 sleep and slow-wave sleep, helping you achieve deeper and more rejuvenating sleep at night:
“After repeated intravenous (i.v.) boluses of growth hormone-releasing peptide-6 (GHRP-6) we found recently increases of growth hormone (GH), corticotropin (ACTH) and cortisol levels and of the amount of stage 2 sleep.
In clinical use, oral (p.o.), intranasal (i.n.) and sublingual (s.l.) routes of administration have advantages over i.v. administration.
We compared the sleep-endocrine effects of 300 μg/kg of body weight (b.w.) GHRP-6 in enteric-coated capsules given p.o. at 21.00 h and of 30 μg/kg GHRP-6 i.n. or 30 μg/kg GHRP-6 sl. given at 22.45 h in normal young male controls with placebo conditions.
After GHRP-6 p.o. secretion of GH, ACTH and cortisol remained unchanged.
The only effect of GHRP-6 s.l. was a trend toward an increase in GH in the first half of the night.
GHRP-6 i.n. prompted a significant increase in GH concentration during the total night and a trend toward an increase in ACTH secretion during the first half of the night, whereas cortisol secretion remained unchanged.
Furthermore, after GHRP-6 i.n., sleep stage 2 increased in the second half of the night by trend, and spectral analysis of total night non-rapid eye movement (REM) sleep revealed a decrease of delta power by trend.
In contrast sleep stage 2 decreased during the second half of the night after GHRP-6 p.o.
Our data demonstrate that GHRP-6 is capable of modulating GH and ACTH secretion as well as sleep. However, the effects depend upon dosage, duration and route of administration.”
CJC-1295, on the other hand, promotes GH secretion.
This results in the same benefits just described: Improved sleep quality and more restorative sleep.
In fact, GHRH peptides like CJC-1295 have been shown to increase slow-wave sleep by up to ten-fold:
‘In the present study, the possible somnogenic effects of intravenous bolus injections of a dose of GHRH eliciting physiological elevations of GH secretion in healthy young men were investigated. GHRH (0.3 micrograms/kg body wt) was given in early sleep [i.e., 1st slow-wave (SW) period], late sleep (i.e., 3rd REM period), and early sleep after sleep deprivation until 0400 h (i.e., 1st SW period).
In the absence of sleep deprivation, injection of GHRH in early sleep did not modify SW sleep but increased REM sleep.
GHRH administration in the third REM period was followed by a marked decrease of wake and an almost 10-fold increase in SW sleep.
When GHRH was administered during the first SW period after sleep deprivation until 0400 h, the duration of wake decreased.
Thus GHRH has sleep-promoting effects in young adults, particularly when given at a time of decreased sleep propensity.”
Dosage and Administration
How much CJC-1295 and Ipamorelin one should use can vary depending on their goals, body composition, and how one responds to the peptides.
To ensure safety and efficacy, you can follow the dosing guidelines below:
- CJC-1295 DAC (long-acting version): 2 mg per week, divided into multiple doses.
- OR: CJC-1295 without DAC (Mod GRF 1-29): 100-300 mcg taken 2-3 times a day.
- Ipamorelin: 100-300 mcg per dose, administered 2-3 times a day.
Begin with lower doses and gradually titrate up, keeping a close eye on how your body reacts.
The goal is to find the lowest effective dose that delivers your desired results with minimal side effects.
Incorrect dosing can lead to potential side effects and/or reduced effectiveness.
Therefore, make sure to consult your doctor to guide you with the correct dosing to ensure safety and effectiveness.
How Long Should You Cycle CJC-1295 and Ipamorelin?
The length of your CJC-1295 and Ipamorelin cycle depends on your goals, but the majority of bodybuilders tend to follow an 8 to 12-week cycle.
This means they use both peptides for 8-12 weeks and then take an 8-12 week break from using either peptide so the body can restore its normal GH production.
To avoid potential side effects, it’s important to avoid abusing these peptides or running them beyond the recommended 8-12 weeks.
This will help you reap the benefits of increased growth hormone levels while reducing the risk of desensitization.
During your cycle, keep diligent track of your progress.
Useful variables to monitor include changes in your muscle mass, fat loss, recovery time, and overall well-being.
This data will help you evaluate the effectiveness of the peptides and decide if you need to adjust your cycle length and/or dosage.
Remember: ALWAYS use peptides responsibly and under the supervision of your doctor.
Potential Side Effects
Just like any peptide, whether alone or taken as part of a stack, the use of the Ipamorelin and CJC-1295 stack without proper supervision and dosing can lead to side effects such as:
- Headaches
- Nausea
- Injection site reactions (since they’re administered subcutaneously)
- Water retention
- Altered cortisol levels
Prolonged and unregulated use can also disrupt hormonal balance, thereby negatively impacting thyroid function and natural growth hormone production.
Some users may experience decreased insulin sensitivity, increased insulin resistance, and high blood sugar levels due to changes in cortisol.
Despite these potential side effects, many find that the benefits of using this peptide stack outweigh the costs.
Real-Life Results and Testimonials
Many men and women use Ipamorelin and CJC-1295 stacked together to boost their muscle gains.
Beyond muscle-building and toning, they also experience other amazing benefits such as weight loss, better sleep, and faster recovery.
Reddit user Immediate-Avocado277 lost 50 pounds while gaining muscle with a CJC-1295 and Ipamorelin stack:
“Yes, add that stack. Very few negative side effects are associated with them. Use it 5 out of 7 days and for a total of 6-8 weeks at a time. I have lost a total of 50 pounds and added a ton of muscle on that plus tirzepatide. I do a total of 480mcg.”
eRoids user BigBmaj experienced faster recovery after 6 months of using both Ipamorelin and CJC-1295 without any side effects:
“I’m following the same protocol. The biggest improvements I’ve seen are 1) amazing recovery 2) cannot gain body fat – no matter what. I’ve been doing it for probably 6 months now.”
I don’t notice a flush in the face with the shots anymore, which is making me think I’ve lost some potency.”
EliteFitness user J223 also stayed lean even while indulging in food excessively:
You will still notice fat loss even with eating more food because the GH effects will keep you lean.
If it’s a big problem for you then make sure to eat lean foods like chicken, fish, or rice/potatoes, and veggies.
I like shooting GHRP then slamming a big can of tuna, which has hardly any fat, zero carbs and 55g protein!
So you can cut even with the appetite increase, you just gotta time the injections before your meals and eat healthy.
Another EliteFitness user, Bird901, used to wake up every two hours at night but is now enjoying deeper and more restful sleep thanks to stacking Ipamorelin and CJC-1295.
“Weighed in this morning at 215.8. My sleep is definitely better with this stuff. I used to wake up every 2 hours.
Only woke up once and felt great when I got up. Upped CJC to 150mcgs every time and Ipamorelin to 200 pwo.”
Lastly, EliteFitness user RottenWillow experienced increased muscle gain after 6 months of using CJC-1295 and Ipamorelin together.
I’ve been running what is essentially exactly the same protocol for 6 months. This GHRP stack will optimize your GH levels, provided you use them properly. Over time they definitely will increase your muscle acquisition rate.
Jay’s Closing Thoughts
I have spoken numerous times about the Ipamorelin and CJC-1295 stack for reasons far beyond muscle gain:
However, I have also briefly mentioned the stack in two separate articles about muscle gain.
The only real caveat is I AM still unconvinced Ipamorelin and CJC-1295 alone are insufficient for inducing anabolism (assuming diet, training, and cardio are on point).
While Ipamorelin and CJC-1295 may be decent at inducing anabolism on paper, you are much better off using them as fat loss and longevity agents.
“…using CJC-1295 and Ipamorelin together will cause water retention in your subcutaneous fat.
Additionally, both peptides are far more useful as agents for fat loss than agents for muscle growth.
I would highly recommend using [this] peptide stack in combination with therapeutic testosterone if you are serious about inducing anabolism.”
Furthermore, CJC-1295 no longer receives my endorsement due to the nasty flushing effect it creates in many users.
Tesamorelin is by and far the superior GHRH and can also be stacked with Ipamorelin to produce a superior output of GH.
Having said all that, pharma-grade HGH still remains miles above any combination of GH-secreting peptides unless the folks at Big Pharma come up with something better.
Long story short?
HGH >>>>>>> Tesamorelin and Ipamorelin > CJC-1295 and Ipamorelin
Leave your muscle-building endeavors to testosterone and HGH instead.
Key Takeaways and Where to Source Ipamorelin & CJC-1295
If you want to lose body fat, gain muscle, and improve your sleep and recovery, stacking Ipamorelin and CJC-1295 is worth an honest effort.
Both peptides optimize your body’s natural GH-related processes, boosting your energy levels and enhancing your body composition.
While Ipamorelin and CJC-1295 can be powerful tools for health and fitness, they work best as part of a well-rounded approach to health that includes proper diet and exercise.
However, as with any performance-enhancing peptides that affect your hormonal health, using excessively high doses and/or using them for too long can lead to unwanted effects.
Therefore, make sure you follow the right dosing and only buy your CJC-1295 and Ipamorelin stack from a reliable vendor.
They have the best formulations of experimental compounds available, and no other vendor comes close to offering them at ultra-high levels of purity for reasonable prices.
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